Sustainable Development Goals

Abstract/Objectives

Craving is a key symptom of substance use disorder (SUD) and a major predictor of relapse. Current craving assessments rely mainly on self-report measures and may be limited by response bias. This pilot study aims to evaluate the feasibility of a novel craving assessment system that integrates virtual reality (VR) technology with wearable sensors. The system simultaneously captures subjective responses and objective physiological signals, including EEG, heart rate variability (HRV), and respiration. A total of 120 individuals with amphetamine use disorder and 40 healthy adults will be recruited. Findings are expected to support the development of a standardized and objective craving assessment approach and advance the application of digital therapeutics in addiction treatment.

Results/Contributions

(1) Development of an Integrated Craving Assessment System:

This study aims to establish an integrated craving assessment system combining virtual reality (VR) technology and wearable physiological sensing devices. Through VR-based cue induction, physiological signals such as electroencephalography (EEG), heart rate variability (HRV), and respiration will be simultaneously collected. By integrating subjective questionnaires with objective physiological indicators, the study seeks to develop a comprehensive assessment model to enhance the objectivity and clinical applicability of craving assessment in addiction treatment.

(2) Establishment of a Research Database and Preliminary Evidence for Intervention:

The study will explore the potential effects of mindfulness intervention on the regulation of craving responses. In addition, an anonymized database consisting of psychological questionnaire data and physiological indicators will be established, providing a foundation for future craving prediction models and the development of digital therapeutics.

(3) Academic and Practical Contributions:

The findings of this study are expected to be submitted to academic journals related to addiction medicine, psychology, or digital health, and presented at national and international conferences. The results may further promote the application of virtual reality and physiological sensing technologies in the fields of mental health and addiction treatment.



Keywords

Substance Use Disorder, Craving Assessment, Virtual Reality, Wearable Sensors, Physiological Signals, Digital Therapeutics